PROTEIN AND DNA BINDING PROPERTIES OF IRON(III)- PYRIDOXAL-S-METHYL-ISO-THIOSEMICARBAZONE (FE(III)-PLITSC) COMPLEX
The antimicrobial activity and cytotoxicity of semicarbazone-metal complexes was described in the literature. The interactions between transport proteins/DNA and newly synthesized Fe(III)-pyridoxal-S-methyl-isothiosemicarbazone (Fe-PLITSC) complex were examined by experimental and theoretical methods, as a way to access the possible distribut...
By Aleksandra A. Rakić, Luka Golubović, Violeta Jevtović, Dušan Dimić
SYNTHESIS AND STRUCTURE OF PYRIDOXAL-S-METHYLISO-THIOSEMICARBAZONE-IRON(III) (PLITSC-FE(III)) COMPLEX
Isothiosemicarbazone molecules are an important part of a thiosemicarbazone family due to their coordination capacity and antiviral, antibacterial, antimalarial, and antitumor bioactivities, especially when coordinated with a metal ion. A new complex of Fe(III) with ligand Pyridoxal-S-methyl-isothiosemicarbazone (PLITSC) is synthesized. The s...
By Aleksandra A. Rakić, Luka Golubović, Violeta Jevtović, Dušan Dimić
ISOPROTERENOL STRUCTURE, ANTIOXIDATIVE PROPERTIES, AND INTERACTIONS WITH PROTEINS
Isoprenaline (isoproterenol) is a non-selective β-adrenoreceptor agonist known for its therapeutic effects, which include increased heart rate and cardiac output, bronchodilation, and improved peripheral circulation. Apart from its primary functions in the nervous system and physiological regulation, isoproterenol exhibits antioxidant pr...
By Aleksandra A. Rakić, Marija D. Milosavljević, Dušan S. Dimić