PROTEIN AND DNA BINDING PROPERTIES OF IRON(III)- PYRIDOXAL-S-METHYL-ISO-THIOSEMICARBAZONE (FE(III)-PLITSC) COMPLEX
The antimicrobial activity and cytotoxicity of semicarbazone-metal complexes was described in the literature. The interactions between transport proteins/DNA and newly synthesized Fe(III)-pyridoxal-S-methyl-isothiosemicarbazone (Fe-PLITSC) complex were examined by experimental and theoretical methods, as a way to access the possible distribut...
By Aleksandra A. Rakić, Luka Golubović, Violeta Jevtović, Dušan Dimić
SYNTHESIS AND STRUCTURE OF PYRIDOXAL-S-METHYLISO-THIOSEMICARBAZONE-IRON(III) (PLITSC-FE(III)) COMPLEX
Isothiosemicarbazone molecules are an important part of a thiosemicarbazone family due to their coordination capacity and antiviral, antibacterial, antimalarial, and antitumor bioactivities, especially when coordinated with a metal ion. A new complex of Fe(III) with ligand Pyridoxal-S-methyl-isothiosemicarbazone (PLITSC) is synthesized. The s...
By Aleksandra A. Rakić, Luka Golubović, Violeta Jevtović, Dušan Dimić