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 The antimicrobial activity and cytotoxicity of semicarbazone-metal complexes was described in the literature. The interactions between transport proteins/DNA and newly synthesized Fe(III)-pyridoxal-S-methyl-isothiosemicarbazone (Fe-PLITSC) complex were examined by experimental and theoretical methods, as a way to access the possible distribut...

By Aleksandra A. Rakić, Luka Golubović, Violeta Jevtović, Dušan Dimić

 Isothiosemicarbazone molecules are an important part of a thiosemicarbazone family due to their coordination capacity and antiviral, antibacterial, antimalarial, and antitumor bioactivities, especially when coordinated with a metal ion. A new complex of Fe(III) with ligand Pyridoxal-S-methyl-isothiosemicarbazone (PLITSC) is synthesized. The s...

By Aleksandra A. Rakić, Luka Golubović, Violeta Jevtović, Dušan Dimić

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