This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Faculty of Science, University of Kragujevac , Kragujevac , Serbia
Faculty of Science, University of Kragujevac , Kragujevac , Serbia
Universidad Politecnica de Madrid , Madrid , Spain
Department in Kragujevac, Kragujevac, Academy of Professional Studies Šumadija Serbia
This research focuses on the dynamics of electron behavior during the laserinduced breakdown (LIB) in skin tissues, pivotal for plasma generation in biomedical contexts. Through a numerical analysis centered on high-intensity Nd:YAG laser pulses within the 500–1000 nm wavelength range and a 10 ns pulse duration, we explore the balance of electron gains and losses. This understanding is crucial for manipulating LIB processes, which play a significant role in innovating medical treatments and diagnostics. Employing a numerical model, our study simulates the evolution of free electron density in skin tissues, considering various ionization mechanisms like multiphoton, cascade, and chromophore ionization, as well as electron diffusion and recombination. The investigation enriches the theoretical base for LIB and offers practical guidance for fine-tuning laser parameters to enhance medical applications. It underscores the contribution of numerical simulations to the advancement of laser technologies in medicine, paving the way for the development of targeted and more efficacious therapeutic interventions.
The statements, opinions and data contained in the journal are solely those of the individual authors and contributors and not of the publisher and the editor(s). We stay neutral with regard to jurisdictional claims in published maps and institutional affiliations.